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Article

5' UTR polymorphism of dopamine receptor D1 (DRD1) associated with severity and temperament of alcoholism.

Biochemical and biophysical research communications - 15 Jun 2007

Kim Dai-Jin, Park Byung Lae, Yoon Sujung, Lee Hae-Kook, Joe Keun-Ho, Cheon Young-Hoon, Gwon Do-Hoon, Cho Sung-Nam, Lee Hye Won, NamGung Suk, Shin Hyoung Doo

Abstract excerpt

Multiple dopamine receptors in the dopaminergic system may be prime candidates for genetic influence on alcohol abuse and dependence due to their involvement in reward and reinforcing mechanisms. Genetic polymorphisms in dopamine receptor genes are believed to influence the development and/or severity of alcoholism. To examine the genetic effects of the Dopamine Receptor D1 (DRD) gene family (DRD1-DRD5) in the...

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Identifiers

PMID: 17466946
DOI: 10.1016/j.bbrc.2007.04.074

Genes

DRD1
DRD5

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