Article
microRNA-422a Inhibits DCC Expression in a Manner Dependent on SNP rs12607853.
Cytogenetic and genome research - 1 Jan 2020
Li Yunxiao, Shi Xugang, Cai Xintong, Zhu Yongsheng, Chen Yuanyuan, Lai Jianghua
Abstract excerpt
DCC netrin 1 receptor (DCC) affects the structure and function of the dopamine circuitry, which in turn affects the susceptibility to developing addiction. In a previous study, we found that single nucleotide polymorphism (SNP) rs12607853 in the 3' untranslated region (3'-UTR) of DCC was significantly associated with heroin addiction. In the current study, we first used bioinformatics prediction to identify the...
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