Article
The impact of VKORC1-1639G > A genetic polymorphism upon warfarin dose requirement in different ethnic populations.
Current medical research and opinion - 1 Aug 2014
Jin Bo, Hong Yong, Zhu Jun, Li Yong, Shi Hai-Ming
Abstract excerpt
OBJECTIVE: Published data on the association between vitamin K epoxide reductase complex 1 (VKORC1)-1639G > A polymorphism and warfarin dose requirement are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. METHODS AND RESULTS: Studies were identified in English-language articles by search of PubMed and Embase database (inception to July 2013). A total of 32...
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