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Article

Serotonergic genes modulate amygdala activity in major depression.

Genes, brain, and behavior - 1 Oct 2007

Dannlowski U, Ohrmann P, Bauer J, Kugel H, Baune B T, Hohoff C, Kersting A, Arolt V, Heindel W, Deckert J, Suslow T

Abstract excerpt

Serotonergic genes have been implicated in the pathogenesis of depression probably via their influence on neural activity during emotion processing. This study used an imaging genomics approach to investigate amygdala activity in major depression as a function of common functional polymorphisms in the serotonin transporter gene (5-HTTLPR) and the serotonin receptor 1A gene (5-HT(1A)-1019C/G). In 27 medicated...

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Share to Amygdala
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Psychiatric Status Rating Scales

Share to Receptor, Serotonin, 5-HT1A

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Share to Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 17284168
DOI: 10.1111/j.1601-183X.2006.00297.x

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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