Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estimation of the effects of smoking and DNA repair capacity on coefficients of a carcinogenesis model for lung cancer.

International journal of cancer - 1 May 2009

Deng Li, Kimmel Marek, Foy Millennia, Spitz Margaret, Wei Qingyi, Gorlova Olga

Abstract excerpt

Numerous prospective and retrospective studies have clearly demonstrated a dose-related increased lung cancer risk associated with cigarette smoking, with evidence also for a genetic component to risk. In this study, using the two-stage clonal expansion stochastic model framework, for the first time we investigated the roles of both genetic susceptibility and smoking history in the initiation, clonal expansion,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Repair

Share to Lung Neoplasms

Share to Models, Biological

Share to Models, Statistical

Share to Risk Assessment

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 19123470
DOI: 10.1002/ijc.24149
PMCID: PMC2749693

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estimation of the effects of smoking and DNA repair capacity on coefficients of a carcinogenesis model for lung cancer.PMID 19123470Read ↗

Different Mechanisms of Cigarette Smoking-Induced Lung Cancer.Semantic proximity Read ↗

The effect of cigarette smoking on lung cancer evolution.Semantic proximity Read ↗

Biophysical modelling of the effects of inhaled radon progeny on the bronchial epithelium for the estimation of the relationships applied in the two-stage clonal expansion model of carcinogenesis.Semantic proximity Read ↗

Biologically-based mechanistic models of radiation-related carcinogenesis applied to epidemiological dataSemantic proximity Read ↗

Mathematical modeling for mutator phenotype and clonal selection advantage in the risk analysis of lung cancer.Semantic proximity Read ↗

Radon-induced lung cancer in smokers and non-smokers: risk implications using a two-mutation carcinogenesis model.Semantic proximity Read ↗

Could removing arsenic from tobacco smoke significantly reduce smoker risks of lung cancer?Semantic proximity Read ↗

Understanding How Smoking Increases Cancer Risk.Semantic proximity Read ↗

Recovery of human upper airway epithelium after smoking cessation is driven by a slow-cycling stem cell population and immune surveillanceSemantic proximity Read ↗

Modelling lung tumour risk in radon-exposed uranium miners using generalizations of the two-mutation model of Moolgavkar, Venzon and Knudson.Semantic proximity Read ↗

Multistage carcinogenesis modeling and the initiation event.Semantic proximity Read ↗

Genetic susceptibility for lung cancer: interactions with gender and smoking history and impact on early detection policies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.