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Article

Modelling lung tumour risk in radon-exposed uranium miners using generalizations of the two-mutation model of Moolgavkar, Venzon and Knudson.

International journal of radiation biology - 1 Jan 2002

Little Mark P, Haylock R G E, Muirhead C R

Abstract excerpt

PURPOSES: To model radon-induced lung cancer in uranium miners using a quasi-biological model of carcinogenesis. MATERIALS AND METHODS: Fitting of generalizations of the stochastic two-mutation carcinogenesis model of Moolgavkar, Venzon and Knudson to a case-control dataset nested within the cohort and to the full cohort of lung cancer mortality in the Colorado Plateau uranium miners, taking account of exposure...

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PMID: 11747553
DOI: 10.1080/09553000110085797

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