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Article

Efficient lowering of triglyceride levels in mice by human apoAV protein variants associated with hypertriglyceridemia.

Biochemical and biophysical research communications - 6 Feb 2009

Vaessen Stefan F C, Sierts Jeroen A, Kuivenhoven Jan Albert, Schaap Frank G

Abstract excerpt

Variation in the apolipoprotein A5 (APOA5) gene has consistently been associated with increased plasma triglyceride (TG) levels in epidemiological studies. In vivo functionality of these variations, however, has thus far not been tested. Using adenoviral over-expression, we evaluated plasma expression levels and TG-lowering efficacies of wild-type human apoAV, two human apoAV variants associated with increased TG...

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Share to Apolipoprotein A-V
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 19121291
DOI: 10.1016/j.bbrc.2008.12.115

Genes

APOA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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