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Article

Apolipoprotein A5, a newly identified gene that affects plasma triglyceride levels in humans and mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2003

Pennacchio Len A, Rubin Edward M

Abstract excerpt

Apolipoprotein A5 (APOA5) is a newly described member of the apolipoprotein gene family whose initial discovery arose from comparative sequence analysis of the mammalian APOA1/C3/A4 gene cluster. Functional studies in mice indicated that alteration in the level of APOA5 significantly affected plasma triglyceride concentrations. Mice that overexpressed human APOA5 displayed significantly reduced triglycerides,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12615678
DOI: 10.1161/01.ATV.0000054194.78240.45

Genes

APOA5
APOA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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