Article
UvrAB activity at a damaged DNA site: is unpaired DNA present?
The EMBO journal - 17 Feb 1997
Gordienko I, Rupp W D
Abstract excerpt
To study the activity of the Escherichia coli UvrA and UvrB nucleotide excision repair proteins during the formation of the pre-incision complex at a damaged DNA site, we used substrates with modifications around a single 2-(acetylamino)fluorene (AAF) lesion. Based on the release of AAF-containin...
Topics
- 2-Acetylaminofluorene
- Adenosine Triphosphatases
- Bacterial Proteins
- DNA Adducts
- DNA Damage
- DNA Helicases
- DNA Repair
- DNA, Single-Stranded
- DNA-Binding Proteins
- Endodeoxyribonucleases
- Escherichia coli
- Escherichia coli Proteins
- Models, Genetic
- Mutation
- Nucleic Acid Conformation
- Nucleic Acid Denaturation
- Oligodeoxyribonucleotides