Article
Haplotype analysis of the PARK 11 gene, GIGYF2, in sporadic Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 15 Feb 2009
Sutherland Greg T, Siebert Gerhard A, Newman Jeremy R B, Silburn Peter A, Boyle Richard S, O'Sullivan John D, Mellick George D
Abstract excerpt
Familial Parkinsonism (PARK) genes are strong candidates for conferring susceptibility to common forms of PD. However, most studies to date have provided little evidence that their common variants substantially influence disease risk. Recently, mutations were described in the gene, GIGYF2 (TNRC15), located at the PARK11 locus (2q37.1). Here, we use a haplotype tagging approach to examine common variation in the...
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