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Article

Mutations in the GIGYF2 (TNRC15) gene at the PARK11 locus in familial Parkinson disease.

American journal of human genetics - 1 Apr 2008

Lautier Corinne, Goldwurm Stefano, Dürr Alexandra, Giovannone Barbara, Tsiaras William G, Pezzoli Gianni, Brice Alexis, Smith Robert J

Abstract excerpt

The genetic basis for association of the PARK11 region of chromosome 2 with familial Parkinson disease (PD) is unknown. This study examined the GIGYF2 (Grb10-Interacting GYF Protein-2) (TNRC15) gene, which contains the PARK11 microsatellite marker with the highest linkage score (D2S206, LOD 5.14). The 27 coding exons of the GIGYF2 gene were sequenced in 123 Italian and 126 French patients with familial PD, plus...

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Identifiers

PMID: 18358451
DOI: 10.1016/j.ajhg.2008.01.015
PMCID: PMC2427211

Genes

GIGYF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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