Article
GIGYF2 Asn56Ser and Asn457Thr mutations in Parkinson disease patients.
Neuroscience letters - 1 May 2009
Guo Yi, Jankovic Joseph, Zhu Shaihong, Le Weidong, Song Zhi, Xie Wenjie, Liao Daoguang, Yang Huarong, Deng Hao
Abstract excerpt
Parkinson disease (PD) is one of the most common neurodegenerative disorders with major clinical features of bradykinesia, rigidity, resting tremor, and postural instability. At least thirteen gene loci responsible for PD or parkinsonism have been found and nine causative genes have been identified. Recently, Asn56Ser or Asn457Thr mutations in the Grb10-Interacting GYF Protein-2 gene (GIGYF2) were found to occur...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.