Article
SUMO4 and MAP3K7IP2 single nucleotide polymorphisms and susceptibility to rheumatoid arthritis.
The Journal of rheumatology - 1 Jun 2006
Costas Javier, Perez-Pampin Eva, Ferreiros-Vidal Isabel, Torres Maria, Phillips Christopher, Vicario Jose Luis, Pablos Jose Luis, Carracedo Angel, Gomez-Reino Juan J, Gonzalez Antonio
Abstract excerpt
OBJECTIVE: To explore the role of single nuclear polymorphisms (SNP) in 2 candidate genes, SUMO4 and MAP3K7IP2, in susceptibility to rheumatoid arthritis (RA). METHODS: Two cohorts from different Spanish towns totalling 635 patients with RA and 826 controls were studied. Six SNP were genotyped by matrix assisted laser desorption-ionization time-of-flight (MALDI-TOF) with the MassARRAY SNP genotyping system....
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