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Article

No evidence of association of the KLF12 gene with rheumatoid arthritis in Spanish and Dutch cohorts and a meta-analysis of published data.

Human immunology - 1 Sept 2011

García-Bermúdez Mercedes, López-Mejias Raquel, Rodriguez-Rodriguez Luis, Fernández-Gutierrez Benjamín, García Antonio, Raya Enrique, Ortiz Ana M, Coenen Marieke J H, van Riel Piet L C M, Radstake Timothy R D J, González-Gay Miguel A, Martín Javier

Abstract excerpt

The aim of the present study was to replicate the previously reported association of KLF12 gene polymorphisms with rheumatoid arthritis (RA). Two independent cohorts from Spain (1,360 RA patients and 1,520 controls) and the Netherlands (1,018 RA patients and 1,150 controls) were genotyped for KLF12 rs1887346 and rs9565072 single-nucleotide polymorphisms using a TaqMan 5'-allele discrimination assay. No evidence...

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Source

Identifiers

PMID: 21658422
DOI: 10.1016/j.humimm.2011.05.006

Genes

KLF12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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