Article
Cdc6 and cyclin E2 are PTEN-regulated genes associated with human prostate cancer metastasis.
Neoplasia (New York, N.Y.) - 1 Jan 2009
Wu Zhong, Cho HyungJun, Hampton Garret M, Theodorescu Dan
Abstract excerpt
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is frequently inactivated in metastatic prostate cancer, yet the molecular consequences of this and their association with the metastatic phenotype are incompletely understood. We performed transcriptomic analysis and identified genes altered by conditional PTEN reexpression in C4-2, a human metastatic prostate cancer cell line with inactive PTEN....
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