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The regulation of PTEN: Novel insights into functions as cancer biomarkers and therapeutic targets

18 Jun 2023

Abstract excerpt

This review summarizes the implications of the primary tumor suppressor protein phosphatase and tensin homolog (PTEN) in aggressive cancer development. PTEN interacts with other cellular proteins or factors suggesting the existence of an intricate molecular network that regulates their oncogenic function. Accumulating evidence has shown that PTEN exists and plays a role in the cytoplasmic organelles and in the...

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Cytokine Signaling Pathways and Interactions
PI3K/AKT/mTOR signaling in cancer
Protein Kinase Regulation and GTPase Signaling

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37334436
DOI: 10.1002/jcp.31053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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