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Article

Interactions between immunogenic peptides and MHC proteins.

Annual review of immunology - 1 Jan 1991

Rothbard J B, Gefter M L

Abstract excerpt

The MHC class-I and class-II molecules are highly polymorphic membrane proteins, which bind and transport to the surface of cells peptide fragments of intact proteins. The peptide-MHC complexes are recognized by the antigen-specific receptor of T lymphocytes and are the basis by which the cellular immune system distinguishes self from nonself. In order to perform this function, MHC proteins simultaneously display...

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Identifiers

PMID: 1910688
DOI: 10.1146/annurev.iy.09.040191.002523

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Source receipt: pubmed, retrieved 7 Sept 2026.

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