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Article

Interactions between immunogenic peptides and MHC proteins.

Annual review of immunology - 1 Jan 1991

Rothbard J B, Gefter M L

Abstract excerpt

The MHC class-I and class-II molecules are highly polymorphic membrane proteins, which bind and transport to the surface of cells peptide fragments of intact proteins. The peptide-MHC complexes are recognized by the antigen-specific receptor of T lymphocytes and are the basis by which the cellular immune system distinguishes self from nonself. In order to perform this function, MHC proteins simultaneously display...

Topics

Alleles
Amino Acid Sequence
Animals
Histocompatibility Antigens
Humans
Molecular Sequence Data
Peptides
Protein Binding

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1910688
DOI: 10.1146/annurev.iy.09.040191.002523

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1910688-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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