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Article

Progesterone Inhibits basal and gonadotropin-releasing hormone induction of luteinizing hormone beta-subunit gene expression.

Endocrinology - 1 May 2009

Thackray Varykina G, Hunnicutt Jennifer L, Memon Aisha K, Ghochani Yasmin, Mellon Pamela L

Abstract excerpt

LH and FSH play critical roles in mammalian reproduction by mediating steroidogenesis and gametogenesis in the gonad. Gonadal steroid hormone feedback to the hypothalamus and pituitary influences production of the gonadotropins. We previously demonstrated that progesterone differentially regulates the expression of the LH and FSH beta-subunits at the level of the gonadotrope: FSHbeta transcription is induced,...

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Identifiers

PMID: 19106225
DOI: 10.1210/en.2008-1027
PMCID: PMC2671912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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