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Article

Control of oocyte release by progesterone receptor-regulated gene expression

1 Jan 2009

Abstract excerpt

The progesterone receptor (PGR) is a nuclear receptor transcription factor that is essential for female fertility, in part due to its control of oocyte release from the ovary, or ovulation. In all mammals studied to date, ovarian expression of PGR is restricted primarily to granulosa cells of follicles destined to ovulate. Granulosa cell expression of PGR is induced by the pituitary Luteinizing Hormone (LH) surge...

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PMID: 20087433
DOI: 10.1621/nrs.07012

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