Article
Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1.
Molecular endocrinology (Baltimore, Md.) - 1 May 2004
Bailey Janice S, Rave-Harel Naama, McGillivray Shauna M, Coss Djurdjica, Mellon Pamela L
Abstract excerpt
FSH is critical for normal reproductive function in both males and females. Activin, a member of the TGFbeta family of growth factors, is an important regulator of FSH expression, but little is known about the molecular mechanisms through which it acts. We used transient transfections into the im...
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