Article
Association between donor MBL promoter haplotype and graft survival and the development of BOS after lung transplantation.
Transplantation - 27 Dec 2008
Munster Janna M, van der Bij Wim, Breukink Myrte B, van der Steege Gerrit, Zuurman Mike W, Hepkema Bouke G, Verschuuren Erik A M, van Son Willem J, Seelen Marc A J
Abstract excerpt
BACKGROUND: Lung transplantation is a well accepted therapy for end-stage lung disease, despite high mortality rates. Mortality after transplantation is mainly caused by allograft failure in the first years after transplantation. Mannose binding lectin (MBL), a recognition molecule of innate immunity, has been associated with transplant outcome in other solid organ transplantation. In this study, the effect of...
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