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Article

Association of polymorphisms of interleukin-8, CXCR1, CXCR2, and selectin with allograft outcomes in kidney transplantation.

Transplantation - 15 Jan 2011

Ro Han, Hwang Young-Hwan, Kim Hyunsook, Jeong Jong Cheol, Lee Hankyu, Doh Young-Seok, Park Hayne Cho, Oh Kook-Hwan, Park Myoung Hee, Ha Jongwon, Yang Jaeseok, Ahn Curie

Abstract excerpt

BACKGROUND: Both chemokines and adhesion molecules mediate allograft rejection by recruiting leukocytes into the allograft. We investigated the association of six single nucleotide polymorphisms (SNPs) located in interleukin (IL)-8, CXCR1, CXCR2, and selectin with kidney allograft outcomes. METHODS: The promoter regions of CXCR1 and CXCR2 were sequenced directly to find SNPs. Reporter gene assay was performed to...

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Identifiers

PMID: 21452410
DOI: 10.1097/tp.0b013e3181fd0195

Genes

CXCR2
CXCR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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