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Article

Mutations at embB codon 306 are an important molecular indicator of ethambutol resistance in Mycobacterium tuberculosis.

Antimicrobial agents and chemotherapy - 1 Mar 2009

Starks Angela M, Gumusboga Aysel, Plikaytis Bonnie B, Shinnick Thomas M, Posey James E

Abstract excerpt

Ethambutol resistance in clinical Mycobacterium tuberculosis isolates is associated primarily with missense mutations in the embB gene. However, recent reports have described the presence of embB mutations, especially those at embB codon 306, in isolates susceptible to ethambutol. To clarify the role of embB mutations in ethambutol resistance, we sequenced the ethambutol resistance-determining region in...

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Identifiers

PMID: 19104018
DOI: 10.1128/AAC.01357-08
PMCID: PMC2650568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Mutations at embB codon 306 are an important molecular indicator of ethambutol resistance in Mycobacterium tuberculosis.PMID 19104018Read ↗

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