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Article

Egr-1 negatively regulates calsequestrin expression and calcium dynamics in ventricular cells.

Cardiovascular research - 1 Mar 2009

Kasneci Amanda, Kemeny-Suss Naomi M, Komarova Svetlana V, Chalifour Lorraine E

Abstract excerpt

AIMS: The transcription factor early growth response-1 (Egr-1) is increased in models of cardiac pathology; however, it is unclear how Egr-1 impacts the heart. We sought to identify how Egr-1 regulates expression of proteins involved in cardiomyocyte calcium homeostasis. METHODS: Protein expressi...

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Source

Identifiers

PMID: 19103607
DOI: 10.1093/cvr/cvn357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19103607-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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