Calreticulin is essential for cardiac development.

doi:10.1083/jcb.144.5.857

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Article

Calreticulin is essential for cardiac development.

The Journal of cell biology - 8 Mar 1999

Mesaeli N, Nakamura K, Zvaritch E, Dickie P, Dziak E, Krause K H, Opas M, MacLennan D H, Michalak M

Abstract excerpt

Calreticulin is a ubiquitous Ca2+ binding protein, located in the endoplasmic reticulum lumen, which has been implicated in many diverse functions including: regulation of intracellular Ca2+ homeostasis, chaperone activity, steroid-mediated gene regulation, and cell adhesion. To understand the ph...

Topics

Animals
Base Sequence
Biological Transport
Calcium
Calcium-Binding Proteins
Calreticulin
Cell Nucleus
DNA Primers
DNA-Binding Proteins
Embryonic and Fetal Development
Heart
Inositol 1,4,5-Trisphosphate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Knockout

Mice, Transgenic

NFATC Transcription Factors

Nuclear Proteins

Phenotype

Source

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Identifiers

PMID: 10085286
DOI: 10.1083/jcb.144.5.857
PMCID: PMC2148186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10085286-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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