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Article

Modulation of sarcoplasmic reticulum calcium release by calsequestrin in cardiac myocytes.

Biological research - 1 Jan 2004

Györke Sandor, Györke Inna, Terentyev Dmitry, Viatchenko-Karpinski Serge, Williams Simon C

Abstract excerpt

Calsequestrin (CASQ2) is a high capacity Ca-binding protein expressed inside the sarcoplasmic reticulum (SR). Mutations in the cardiac calsequestrin gene (CASQ2) have been linked to arrhythmias and sudden death induced by exercise and emotional stress. We have studied the function of CASQ2 and the consequences of arrhythmogenic CASQ2 mutations on intracellular Ca signalling using a combination of approaches of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15709687
DOI: 10.4067/s0716-97602004000400014

Genes

CASQ2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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