Article
Genetic interplays between Msx2 and Foxn1 are required for Notch1 expression and hair shaft differentiation.
Developmental biology - 15 Feb 2009
Cai Jing, Lee Jonghyeob, Kopan Raphael, Ma Liang
Abstract excerpt
Hair shafts are produced from stem cells located in the bulge. Our knowledge of the genetic pathways regulating cell fate acquisition in the immediate descendents of these stem cells, and fate maintenance in their committed progeny, is still incomplete. One pathway involved in fate maintenance within the hair matrix is the Notch pathway. Here we use compound genetic mutants to demonstrate that two transcription...
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