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Article

Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.

Development (Cambridge, England) - 1 Jun 2008

Zhang Yuhang, Andl Thomas, Yang Steven H, Teta Monica, Liu Fei, Seykora John T, Tobias John W, Piccolo Stefano, Schmidt-Ullrich Ruth, Nagy Andras, Taketo Makoto M, Dlugosz Andrzej A, Millar Sarah E

Abstract excerpt

beta-Catenin signaling is required for hair follicle development, but it is unknown whether its activation is sufficient to globally program embryonic epidermis to hair follicle fate. To address this, we mutated endogenous epithelial beta-catenin to a dominant-active form in vivo. Hair follicle p...

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Share to beta Catenin
Share to Embryo, Mammalian
Share to Epidermis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Hair Follicle

Share to Mice, Transgenic

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Share to Signal Transduction

Source

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Identifiers

PMID: 18480165
DOI: 10.1242/dev.017459
PMCID: PMC2516408

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18480165-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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