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Article

Embryonic hair follicle fate change by augmented beta-catenin through Shh and Bmp signaling.

Development (Cambridge, England) - 1 Feb 2009

Suzuki Kentaro, Yamaguchi Yuji, Villacorte Mylah, Mihara Kenichiro, Akiyama Masashi, Shimizu Hiroshi, Taketo Makoto M, Nakagata Naomi, Tsukiyama Tadasuke, Yamaguchi Terry P, Birchmeier Walter, Kato Shigeaki, Yamada Gen

Abstract excerpt

beta-catenin signaling is one of the key factors regulating the fate of hair follicles (HFs). To elucidate the regulatory mechanism of embryonic HF fate determination during epidermal development/differentiation, we analyzed conditional mutant mice with keratinocytes expressing constitutively active beta-catenin (K5-Cre Catnb(ex3)fl/+). The mutant mice developed scaly skin with a thickened epidermis and showed...

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PMID: 19141668
DOI: 10.1242/dev.021295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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