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Article

Learning from nudity: lessons from the nude phenotype.

Experimental dermatology - 1 Nov 2005

Mecklenburg Lars, Tychsen Birte, Paus Ralf

Abstract excerpt

In mice, rats, and humans, loss of function of Foxn1, a member of the winged helix/forkhead family of transcription factors, leads to macroscopic nudity and an inborn dysgenesis of the thymus. Nude (Foxn1(nu)/Foxn1(nu)) mice develop largely normal hair follicles and produce hair shafts. However, presumably because of a lack of certain hair keratins, the hair shafts that are generated twist and coil in the hair...

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Identifiers

PMID: 16232301
DOI: 10.1111/j.1600-0625.2005.00362.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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