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Article

Host defense against cholera toxin is strongly CD4+ T cell dependent.

Infection and immunity - 1 Oct 1991

Hörnqvist E, Goldschmidt T J, Holmdahl R, Lycke N

Abstract excerpt

This study investigates the role of CD4+ T cells in host defense against cholera enterotoxin-induced diarrhea. Antitoxin immunoglobulin A formation and gut protection against cholera toxin (CT) following oral immunizations with CT were evaluated in normal mice and mice that had been depleted of CD4+ T cells by in vivo treatment with specific anti-CD4 monoclonal antibodies. Flow cytometer analysis demonstrated...

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Identifiers

PMID: 1910010
DOI: 10.1128/iai.59.10.3630-3638.1991
PMCID: PMC258931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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