Article

Characterization and utility of novel monoclonal antibodies to cholera toxin B subunit

2022-11-04

Abstract excerpt

Cholera toxin B subunit (CTB) is a potent immunomodulator exploitable in mucosal vaccine and immunotherapeutic development. To aid in the characterization of pleiotropic biological functions of CTB and its variants, we generated a panel of anti-CTB monoclonal antibodies (mAbs). By ELISA and surface plasmon resonance, two mAbs, 7A12B3 and 9F9C7, were analyzed for their binding affinities to cholera holotoxin (CTX),...

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Literature Corpus work: bb09f2cd-66b7-5efa-adfc-d86e33ccc81f
DOI: 10.21203/rs.3.rs-2206692/v1

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