Article

Characterization and utility of novel monoclonal antibodies to cholera toxin B subunit

2022-11-04

Abstract excerpt

Cholera toxin B subunit (CTB) is a potent immunomodulator exploitable in mucosal vaccine and immunotherapeutic development. To aid in the characterization of pleiotropic biological functions of CTB and its variants, we generated a panel of anti-CTB monoclonal antibodies (mAbs). By ELISA and surface plasmon resonance, two mAbs, 7A12B3 and 9F9C7, were analyzed for their binding affinities to cholera holotoxin (CTX),...

Identifiers and source

Literature Corpus work: bb09f2cd-66b7-5efa-adfc-d86e33ccc81f
DOI: 10.21203/rs.3.rs-2206692/v1

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