Article
Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis.
Genetics - 1 Jun 2003
Greene Elizabeth A, Codomo Christine A, Taylor Nicholas E, Henikoff Jorja G, Till Bradley J, Reynolds Steven H, Enns Linda C, Burtner Chris, Johnson Jessica E, Odden Anthony R, Comai Luca, Henikoff Steven
Abstract excerpt
Chemical mutagenesis has been the workhorse of traditional genetics, but it has not been possible to determine underlying rates or distributions of mutations from phenotypic screens. However, reverse-genetic screens can be used to provide an unbiased ascertainment of mutation statistics. Here we report a comprehensive analysis of approximately 1900 ethyl methanesulfonate (EMS)-induced mutations in 192 Arabidopsis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.