Article
Discovery of induced point mutations in maize genes by TILLING.
BMC plant biology - 28 Jul 2004
Till Bradley J, Reynolds Steven H, Weil Clifford, Springer Nathan, Burtner Chris, Young Kim, Bowers Elisabeth, Codomo Christine A, Enns Linda C, Odden Anthony R, Greene Elizabeth A, Comai Luca, Henikoff Steven
Abstract excerpt
BACKGROUND: Going from a gene sequence to its function in the context of a whole organism requires a strategy for targeting mutations, referred to as reverse genetics. Reverse genetics is highly desirable in the modern genomics era; however, the most powerful methods are generally restricted to a few model organisms. Previously, we introduced a reverse-genetic strategy with the potential for general applicability...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.