Article
The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.
Breast cancer research : BCR - 1 Jan 2008
Tapper William, Hammond Victoria, Gerty Sue, Ennis Sarah, Simmonds Peter, Collins Andrew, Eccles Diana
Abstract excerpt
INTRODUCTION: Common variants that alter breast cancer risk are being discovered. Here, we determine how these variants influence breast cancer prognosis, risk and tumour characteristics. METHODS: We selected 1,001 women with early onset nonfamilial invasive breast cancer from the Prospective study of Outcomes in Sporadic versus Hereditary breast cancer (POSH) cohort and genotyped 206 single nucleotide...
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