Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes.

doi:10.1007/s10549-011-1663-3

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes.

Breast cancer research and treatment - 1 Jun 2012

Riaz Muhammad, Berns Els M J J, Sieuwerts Anieta M, Ruigrok-Ritstier Kirsten, de Weerd Vanja, Groenewoud Arwin, Uitterlinden Andrè G, Look Maxime P, Klijn Jan G M, Sleijfer Stefan, Foekens John A, Martens John W M

Abstract excerpt

To understand the biology of low-risk breast cancer alleles, and to investigate whether these loci also contribute to disease progression that was once established, we examined the association of SNPs tagging the low-risk breast cancer loci in or near FGFR2, LSP1, MAP3K1, H19, TOX3, POU5F1P1, MYC, and 2q35, with clinical, pathological characteristics, prognosis, and mRNA expression of the nearest genes. Tumor DNA...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Breast Neoplasms
Disease-Free Survival
Female
Gene Frequency
Genetic Loci
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

Middle Aged

Neoplasm Metastasis

Polymorphism, Single Nucleotide

Prognosis

Transcription, Genetic

Young Adult

Source

Open in PubMed

Identifiers

PMID: 21748294
DOI: 10.1007/s10549-011-1663-3

Genes

TOX3
FGFR2
LSP1
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes.PMID 21748294Read ↗

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics.Semantic proximity Read ↗

Clinical correlates of low-risk variants in FGFR2, TNRC9, MAP3K1, LSP1 and 8q24 in a Dutch cohort of incident breast cancer cases.Semantic proximity Read ↗

Low-risk susceptibility alleles in 40 human breast cancer cell lines.Semantic proximity Read ↗

The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients.Semantic proximity Read ↗

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.Semantic proximity Read ↗

Low-risk variants FGFR2, TNRC9 and LSP1 in German familial breast cancer patients.Semantic proximity Read ↗

Breast cancer susceptibility variants alter risks in familial disease.Semantic proximity Read ↗

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Polymorphism at 19q13.41 Predicts Breast Cancer Survival Specifically after Endocrine Therapy.Semantic proximity Read ↗

Association of breast cancer risk loci with breast cancer survival.Semantic proximity Read ↗

The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.Semantic proximity Read ↗

Rare HRAS alleles and susceptibility to human breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.