Article
A genome wide meta-analysis study for identification of common variation associated with breast cancer prognosis.
PloS one - 1 Jan 2014
Rafiq Sajjad, Khan Sofia, Tapper William, Collins Andrew, Upstill-Goddard Rosanna, Gerty Susan, Blomqvist Carl, Aittomäki Kristiina, Couch Fergus J, Liu Jianjun, Nevanlinna Heli, Eccles Diana
Abstract excerpt
OBJECTIVE: Genome wide association studies (GWAs) of breast cancer mortality have identified few potential associations. The concordance between these studies is unclear. In this study, we used a meta-analysis of two prognostic GWAs and a replication cohort to identify the strongest associations and to evaluate the loci suggested in previous studies. We attempt to identify those SNPs which could impact overall...
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