Article
Positive association of CYP11B2 gene polymorphism with genetic predisposition to essential hypertension.
Journal of human hypertension - 1 Nov 2002
Tsukada K, Ishimitsu T, Teranishi M, Saitoh M, Yoshii M, Inada H, Ohta S, Akashi M, Minami J, Ono H, Ohrui M, Matsuoka H
Abstract excerpt
Predispositions to essential hypertension and cardiovascular diseases are possibly associated with gene polymorphisms of the renin-angiotensin system. Gene polymorphisms of angiotensinogen and angiotensin-converting enzyme genes have been suggested to be risk factors for hypertension and myocardial infarction. Concerning the polymorphism of aldosterone synthase (CYP11B2) gene, earlier studies have shown...
Topics
- Adult
- Angiotensinogen
- Cytochrome P-450 CYP11B2
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Hypertension
- Male
- Middle Aged
- Polymorphism, Genetic
