Article
Frequency and nature of cytokine gene polymorphisms in type 1 autoimmune hepatitis.
Hepatology (Baltimore, Md.) - 1 Oct 1999
Cookson S, Constantini P K, Clare M, Underhill J A, Bernal W, Czaja A J, Donaldson P T
Abstract excerpt
Genetic involvement in type 1 autoimmune hepatitis (AIH) is indicated by a marked female preponderance and strong, well-established, human leukocyte antigen (HLA) associations. These associations, however, are not universal and a number of genes outside the major histocompatibility complex may also play a role in susceptibility to type 1 AIH. Prime candidates at present are those polymorphic genes encoding the...
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