Article
Cytokine polymorphisms associated with clinical features and treatment outcome in type 1 autoimmune hepatitis.
Gastroenterology - 1 Sept 1999
Czaja A J, Cookson S, Constantini P K, Clare M, Underhill J A, Donaldson P T
Abstract excerpt
BACKGROUND & AIMS: Polymorphisms that control cytokine production can affect immunoregulation. The frequency and consequences of these polymorphisms in type 1 autoimmune hepatitis were determined. METHODS: DNA samples from 155 patients and 102 ethnically similar normal individuals were assessed by polymerase chain reaction for polymorphisms of 4 different cytokine-producing genes. RESULTS: Only genotypes...
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