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Article

Cytokines genes polymorphisms in chronic hepatitis C: impact on susceptibility to infection and response to therapy.

Cytokine - 1 Feb 2013

Pasha Heba F, Radwan Mohamed I, Hagrass Hoda A, Tantawy Enas A, Emara Mohamed H

Abstract excerpt

BACKGROUND: Cytokines play a key role in the regulation of immune responses. In hepatitis C virus infection, the production of abnormal cytokine levels appears to contribute in the progression of the disease, viral persistence, and affects response to therapy. Cytokine genes polymorphisms located within the coding/regulatory regions have been shown to affect the overall expression and secretion of cytokines. The...

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PMID: 23219017
DOI: 10.1016/j.cyto.2012.11.003

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TNF

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