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Article

Association of cytokine and DNA repair gene polymorphisms with hepatitis B-related hepatocellular carcinoma.

International journal of epidemiology - 1 Dec 2005

Chen Chun-Chieh, Yang Shi-Yi, Liu Chun-Jen, Lin Chih-Lin, Liaw Yun-Fan, Lin Shi-Ming, Lee Shou-Dong, Chen Pei-Jer, Chen Chien-Jen, Yu Ming-Whei

Abstract excerpt

BACKGROUND: Hepatitis B virus (HBV) induces hepatocellular carcinoma (HCC) mainly by causing chronic necroinflammatory hepatic disease. We investigated the mechanisms underlying the inflammatory hepatocarcinogenesis by examining whether genetic variations in cytokines, antioxidant enzymes, and DNA repair genes affect the HCC risk. METHODS: We analyzed 10 polymorphisms in the genes for interleukin-1beta (IL-1B),...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16172101
DOI: 10.1093/ije/dyi191

Genes

TNF
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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