Article
Combined polymorphisms of tumour necrosis factor alpha and interleukin-10 genes in patients with alcoholic hepatitis.
European journal of gastroenterology & hepatology - 1 Jun 2006
Richardet Jean-Philippe, Scherman Elisabeth, Costa Catherine, Campillo Bernard, Bories Phuong-Nhi
Abstract excerpt
OBJECTIVES: The development and progression of alcoholic hepatitis are controlled by an extensive cytokine network which involves pro-inflammatory and anti-inflammatory cytokines. Genetic variations determining production of these cytokines have been described and the susceptibility to the disease may be determined by an imbalance in the expression of several candidate genes. METHODS: We have studied biallelic...
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