Article
Rapid selection of drug-resistant HIV-1 during the first months of suppressive ART in treatment-naive patients.
AIDS (London, England) - 30 Mar 2007
Metzner Karin J, Allers Kristina, Rauch Pia, Harrer Thomas
Abstract excerpt
OBJECTIVE: Efficient antiretroviral therapy (ART) of HIV-1 infection reduces the viral load to undetectable levels and restores the immune system. However, therapy failure appears in a substantial fraction of patients and is mostly associated with the appearance of drug-resistant viruses. It is still not clear when the drug pressure leads to the earliest selection and appearance of drug-resistant HIV-1...
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