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Article

Effects of HFE C282Y and H63D polymorphisms and polygenic background on iron stores in a large community sample of twins.

American journal of human genetics - 1 Apr 2000

Whitfield J B, Cullen L M, Jazwinska E C, Powell L W, Heath A C, Zhu G, Duffy D L, Martin N G

Abstract excerpt

The aim of this study was to assess and to compare the role of HFE polymorphisms and other genetic factors in variation in iron stores. Blood samples were obtained from 3,375 adult male and female twins (age range 29-82 years) recruited from the Australian Twin Registry. There were 1,233 complete pairs (562 monozygotic and 571 dizygotic twins). Serum iron, transferrin, transferrin saturation with iron, and...

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Identifiers

PMID: 10739755
DOI: 10.1086/302862
PMCID: PMC1288192

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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