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Article

SOCS36E specifically interferes with Sevenless signaling during Drosophila eye development.

Developmental biology - 1 Feb 2009

Almudi Isabel, Stocker Hugo, Hafen Ernst, Corominas Montserrat, Serras Florenci

Abstract excerpt

During the development of multicellular organisms the fate of individual cells is specified with great precision and reproducibility. Although classical genetic approaches led to the identification of many of the signaling pathways contributing to cell fate specification, they have provided little insight into the mechanisms that ensure robustness and reproducibility. We have used the specification of the R7...

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Identifiers

PMID: 19083999
DOI: 10.1016/j.ydbio.2008.11.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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SOCS36E specifically interferes with Sevenless signaling during Drosophila eye development.PMID 19083999Read ↗

<i>Drosophila</i>SOCS36E negatively regulates JAK/STAT pathway signaling via two separable mechanismsSemantic proximity Read ↗

Socs36E limits STAT signaling via Cullin2 and a SOCS-box independent mechanism in the Drosophila egg chamber.Semantic proximity Read ↗

The SH2-containing tyrosine phosphatase corkscrew is required during signaling by sevenless, Ras1 and Raf.Semantic proximity Read ↗

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DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila.Semantic proximity Read ↗

Mutations that impair Eyes absent tyrosine phosphatase activity in vitro reduce robustness of retinal determination gene network output in Drosophila.Semantic proximity Read ↗

An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro.Semantic proximity Read ↗

Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila.Semantic proximity Read ↗

Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation.Semantic proximity Read ↗

Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila.Semantic proximity Read ↗

Specification of cell fate in the developing eye of Drosophila.Semantic proximity Read ↗

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