Article
Non-cell-autonomous inhibition of photoreceptor development by Dip3.
Developmental biology - 1 Nov 2008
Duong Hao A, Nagaraj Raghavendra, Wang Cheng W, Ratnaparkhi Girish, Sun Y Henry, Courey Albert J
Abstract excerpt
We show here that the Drosophila MADF/BESS domain transcription factor Dip3, which is expressed in differentiating photoreceptors, regulates neuronal differentiation in the compound eye. Loss of Dip3 activity in photoreceptors leads to an extra photoreceptor in many ommatidia, while ectopic expression of Dip3 in non-neuronal cells results in photoreceptor loss. These findings are consistent with the idea that...
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