Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila.

doi:10.1016/0301-0082(94)90067-1

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Article

Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila.

Progress in neurobiology - 1 Feb 1994

Hafen E, Dickson B, Brunner D, Raabe T

Abstract excerpt

The specification of the R7 photoreceptor cell fate in the developing eye of Drosophila depends on the local activation of the sevenless (sev) receptor tyrosine kinase by boss, a protein expressed on the membrane of the neighboring R8 cell. Constitutive activation of the sev receptor results in a...

Topics

Animals
Drosophila
Eye
Mutation
Ocular Physiological Phenomena
Photoreceptor Cells, Invertebrate
Receptor Protein-Tyrosine Kinases
Signal Transduction

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