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Article

Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Jun 1993

Hafen E, Dickson B, Brunner T, Raabe T

Abstract excerpt

The specification of the R7 photoreceptor cell fate in the developing eye of Drosophila depends on the local activation of the sevenless (Sev) receptor tyrosine kinase by Boss, a protein expressed on the membrane of the neighbouring R8 cell. Constitutive activation of the Sev receptor results in a dosage-dependent increase in the number of R7 cells per ommatidium. Genetic screens have been used to identify...

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Identifiers

PMID: 8103929
DOI: 10.1098/rstb.1993.0068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila.PMID 8103929Read ↗

Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila.Semantic proximity Read ↗

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Specification of cell fate in the developing eye of Drosophila.Semantic proximity Read ↗

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