Article
The corticospinal tract attains a normal configuration in the absence of myelin: observations in jimpy mutant mice.
Neuron - 1 Aug 1991
Stanfield B B
Abstract excerpt
The corticospinal projection was examined in dysmyelinated, jimpy mice and in unaffected littermates following cortical injections of either wheat germ agglutinin conjugated to horseradish peroxidase or biocytin. Corticospinal axons in both phenotypes traverse the medulla within a well-defined pyramidal tract, decussate within several fascicles at the spinomedullary junction, and extend down the spinal cord in a...
Topics
- Animals
- Axons
- Female
- Horseradish Peroxidase
- Lysine
- Male
- Mice
- Mice, Jimpy
- Microscopy
- Myelin Sheath
- Phenotype
- Pyramidal Tracts
- Wheat Germ Agglutinins